Jack Andraka and I Have a Chat!

photo(1)Folks, today I have a rare privilege which I want to share with you. Not that long ago, I reached out to a certain brilliant mind that’s been making waves in the scientific community of late, a young man who – despite his age – has been producing some life saving technologies and leading his own research team. This young man, despite his busy schedule, managed to get back to me quite quickly, and agreed to an interview.

I am of coarse referring to Jack Andraka, a man who’s medical science credentials are already pretty damn impressive. At the age of 16, he developed a litmus test that was capable of detecting pancreatic cancer, one that was 90% accurate, 168 times faster than current tests, and 1/26,000th the cost. For this accomplishment, he won first place at the 2012 Intel International Science and Engineering Fair (ISEF).

Winning at the 2012 ISEF
Winning at the 2012 ISEF

Afterward, he and the other finalists formed their own research group known as Generation Z, which immediately began working towards the creation of a handheld non-invasive device that could help detect cancer early on. In short, they began working on a tricorder-like device, something for which they hope to collect the Tricorder X PRIZE in the near future.

While this project is ongoing, Andraka presented his own concept for a miniature cancer-detecting device at this year’s ISEF. The device is based on a raman spectrometer, but relies on off-the-shelf components like a laser pointer and an iPod camera to scan tissue for cancer cells. And whereas a raman spectrometer is the size of a small car and can cost upwards of $100,000, his fits in the palm of your hand and costs about $15.

Talking with the Prez
Talking with the Prez

Oh, and I should also mention that Jack got to meet President Obama. When I asked what the experience was like, after admitting to being jealous, he told me that the President “loves to talk about science and asks great questions. [And] he has the softest hands!” Who knew? In any case, here’s what he had to tell me about his inspirations, plans, and predictions for the future.

1. What drew you to science and scientific research in the first place?

I have always enjoyed asking questions and thinking about how and why things behave the way they do. The more I learned about a subject, the more deeply I wanted to explore and that led to even more questions. Even when I was 3 I loved building small dams in streams and experimenting with what would happen if I built the dams a certain way and what changes in water flow would occur.

When I entered 6th grade, science fair was required and was very competitive. I was in a charter school and the science fair was really the highlight of the year. Now I did not only love science, but I was highly motivated to do a really good project!

That's him, building is dams.
That’s him, building his dams

2. You’re litmus test for pancreatic cancer was a major breakthrough. How did you come up with the idea for it?

When I was 14 a close family friend who was like an uncle to me passed away from pancreatic cancer. I didn’t even know what a pancreas was so I turned to every teenager’s go-to source of information, Google and Wikipedia, to learn more. What I found shocked me. The 5 year survival rate is just awful, with only about 5.5% of people diagnosed achieving that time period. One reason is that the disease is relatively asymptomatic and thus is often diagnosed when a patient is in an advanced stage of the cancer. The current methods are expensive and still miss a lot of cancers.

I knew there had to be a better way so I started reading and learning as much as I could. One day in Biology class I was half listening to the teacher talk about antibodies while I was reading a really interesting article on carbon nanotubes. Then it hit me: what if I combined what I was reading (single walled carbon nanotubes) with what I was supposed to be listening to (antibodies) and used that mixture to detect pancreatic cancer.

andraka_profileOf course I had a lot of work left to do so I read and read and thought and thought and finally came up with an idea. I would dip coat strips of inexpensive filter paper with a mixture of single walled carbon nanotubes and the antibody to mesothelin, a biomarker for pancreatic cancer. When mesothelin containing samples were applied the antibody would bind with the mesothelin and push the carbon nanotubes apart, changing the strips’ electrical properties, which I could then measure with an ohm meter borrowed from my dad.

Then I realized I needed a lab (my mom is super patient but I don’t think she’d be willing to have cancer research done in her kitchen!). I wrote up a proposal and sent it out to 200 professors working on anything to do with pancreatic research. Then I sat back waiting for the acceptances to roll in.

I received 199 rejections and one maybe, from Dr Maitra of Johns Hopkins School of Medicine. I met with him and he was kind enough to give me a tiny budget and a small space in his lab. I had many many setbacks but after 7 months, I finally created a sensor that could detect mesothelin and thus pancreatic cancer for 3 cents in 5 minutes.

ISEF2012-Top-Three-Winners3. What was your favorite thing about the 2012 Intel International Science and Engineering Fair – aside from winning, of course?

My brother had been a finalist at Intel ISEF and I attended as an observer. I was blown away by the number and quality of the projects there and loved talking to the other finalists. It became my dream to attend Intel ISEF as well. My favorite thing about getting to be a finalist was the sense that I was among kids who were as passionate about math and science as I was and who were curious and creative and who wanted to innovate and push their limits. It felt like I had found my new family! People understood each other and shared ideas and it was so exciting and inspiring to be there with them, sharing my ideas as well!

4. What was the inspiration behind you and your colleagues coming together to start “Generation Z”?

I met some other really interesting kids at Intel ISEF who were making huge advances. I am fascinated by creating ways to diagnose diseases and pollutants. We started talking and the subject of the X Prize came up. We thought it would be a fun challenge to try our hand at it! We figure at the very least we will gain valuable experience working on a team project while learning more about what interests us.

5. How did people react to your smartphone-sized cancer detector at this years ISEF?

Of course people came over to see my project because of my success the previous year. This project was not as finished as it could have been because I was so busy traveling and speaking, but it was great to see all my friends and make new ones and explain what I was aiming for.

Tricorder X6. Your plans for a tricorder that will compete in Tricoder X are currently big news. Anything you can tell us about it at this time?

My team is really coming together. Everyone is working on his/her own piece and then we often Skype and discuss what snags we are running up against or what new ideas we are thinking about.

7. When you hear the words “The Future of Medicine”, what comes to mind? What do you think the future holds?

I believe that the future of medicine is advancing so fast because of the internet and now mobile phones. There are so many new and inexpensive diagnostic methods coming out every month. Hopefully the open access movement will allow everyone access to the knowledge they need to innovate by removing the expensive pay walls that lock away journal articles and the important information they contain from people like me who can’t afford them.

Tricorder X_prizeNow kids don’t have to depend on the local library to have a book that may be outdated or unavailable. They can turn to the internet to connect with MOOCs (Massive Open Online Courses), professors, forums and major libraries to gain the information they need to innovate.

8. What are your plans for the future?

I plan to finish my last 2 years of high school and then go to college. I’m not sure which college or exactly what major yet but I can’t wait to get there and learn even more among other people as excited about science as I am.

9. Last question: favorite science-fiction/fantasy/zombie or superhero franchises of all time, and why do you like them?

I like the Iron Man movies the best because the hero is an amazing scientist and engineer and his lab is filled with everything he would ever need. I wonder if Elon Musk has a lab like that in his house!!

Yeah, that sounds about right! I’m betting you and Musk will someday be working together, and I can only pray that a robotic exoskeleton is one of the outcomes! And I would be remiss if I didn’t point out that we had a Superhero Challenge here on this site, where we designed our own characters and created a fictional crime-fighting league known as The Revengers! We could use a scientifically-gifted mind in our ranks, just saying…

Thank you for coming by and sharing your time with us Jack! I understood very little of what you said, but I enjoyed hearing about it. I think I speak for us all when I say good luck with all your future endeavors, and may all your research pursuits bear fruit!

The Future of the Classroom

virtual_learning2As an educator, technological innovation is a subject that comes up quite often. Not only are teachers expected to keep up with trends so they can adapt them into their teaching strategies, classrooms,and prepare children in how to use them, they are also forced to contend with how these trends are changing the very nature of education itself. If there was one thing we were told repeatedly in Teacher’s College, it was that times are changing, and we must change along with them.

And as history has repeatedly taught us, technological integration not only changes the way we do things, but the way we perceive things. As we come to be more and more dependent on digital devices, electronics and wireless communications to give us instant access to a staggering amount of technology, we have to be concerned with how this will effect and even erode traditional means of information transmission. After all, how can reading and lecture series’ be expected to keep kid’s attention when they are accustomed to lighting fast videos, flash media, and games?

envisioning-the-future-of-education

And let’s not forget this seminal infographic, “Envisioning the future of educational technology” by Envisioning Technology. As one of many think tanks dedicated to predicting tech-trends, they are just one of many voices that is predicting that in time, education will no longer require the classroom and perhaps even teachers, because modern communications have made the locale and the leader virtually obsolete.

Pointing to such trends as Massive Open Online Courses, several forecasters foresee a grand transformation in the not too distant future where all learning happens online and in virtual environments. These would be based around “microlearning”, moments where people access the desired information through any number of means (i.e. a google search) and educate themselves without the need for instruction or direction.

virtual_learning3The technical term for this future trend is Socialstructured Learning = an aggregation of microlearning experiences drawn from a rich ecology of content and driven not by grades but by social and intrinsic rewards. This trend may very well be the future, but the foundations of this kind of education lie far in the past. Leading philosophers of education–from Socrates to Plutarch, Rousseau to Dewey–talked about many of these ideals centuries ago. The only difference is that today, we have a host of tools to make their vision reality.

One such tool comes in the form of augmented reality displays, which are becoming more and more common thanks to devices like Google Glass, the EyeTap or the Yelp Monocle. Simply point at a location, and you are able to obtain information you want about various “points of interest”. Imagine then if you could do the same thing, but instead receive historic, artistic, demographic, environmental, architectural, and other kinds of information embedded in the real world?

virtual_learningThis is the reasoning behind projects like HyperCities, a project from USC and UCLA that layers historical information on actual city terrain. As you walk around with your cell phone, you can point to a site and see what it looked like a century ago, who lived there, what the environment was like. The Smithsonian also has a free app called Leafsnap, which allows people to identify specific strains of trees and botany by simply snapping photos of its leaves.

In many respects, it reminds me of the impact these sorts of developments are having on politics and industry as well. Consider how quickly blogging and open source information has been supplanting traditional media – like print news, tv and news radio. Not only are these traditional sources unable to supply up-to-the-minute information compared to Twitter, Facebook, and live video streams, they are subject to censorship and regulations the others are not.

Attractive blonde navigating futuristic interfaceIn terms of industry, programs like Kickstarter and Indiegogo – crowdsources, crowdfunding, and internet-based marketing – are making it possible to sponsor and fund research and development initiatives that would not have been possible a few years ago. Because of this, the traditional gatekeepers, aka. corporate sponsors, are no longer required to dictate the pace and advancement of commercial development.

In short, we are entering into a world that is becoming far more open, democratic, and chaotic. Many people fear that into this environment, someone new will step in to act as “Big Brother”, or the pace of change and the nature of the developments will somehow give certain monolithic entities complete control over our lives. Personally, I think this is an outmoded fear, and that the real threat comes from the chaos that such open control and sourcing could lead to.

Is humanity ready for democratic anarchy – aka. Demarchy (a subject I am semi-obsessed with)? Do we even have the means to behave ourselves in such a free social arrangement? Opinion varies, and history is not the best indication. Not only is it loaded with examples of bad behavior, previous generations didn’t exactly have the same means we currently do. So basically, we’re flying blind… Spooky!

Sources: fastcoexist.com, envisioningtech.com