The Future is Here: “Terminator-style” Liquid Metal Treatment

t1000_1For ideal physical rehab, it might be necessary to go a little “cyborg”. That’s the reasoning a Chinese biomedical firm used to develop a new method of repairing damaged nerve endings. Borrowing a page from Terminator 2, their new treatment calls for the use of liquid metal to transmit nerve signals across the gap created in severed nerves. The work, they say, raises the prospect of new treatment methods for nerve damage and injuries.

Granted, it’s not quite on par with the liquid-metal-skinned cyborgs from the future, but it is a futuristic way of improving on current methods of nerve rehab that could prevent long-term disabilities. When peripheral nerves are severed, the loss of function leads to atrophy of the effected muscles, a dramatic change in quality of life and, in many cases, a shorter life expectancy. Despite decades of research, nobody has come up with an effective way to reconnect them yet.

nerveVarious techniques exist to sew the ends back together or to graft nerves into the gap that is created between severed ends. And the success of these techniques depends on the ability of the nerve ends to grow back and knit together. But given that nerves grow at the rate of one mm per day, it can take a significant amount of time (sometimes years) to reconnect. And during this time, the muscles can degrade beyond repair and lead to long-term disability.

As a result, neurosurgeons have long hoped for a way to keep muscles active while the nerves regrow. One possibility is to electrically connect the severed ends so that the signals from the brain can still get through; but up until now, an effective means of making this happen has remained elusive. For some time, biomedical engineers have been eyeing the liquid metal alloy gallium-indium-selenium for some time as a possible solution – a material that is liquid at body temperature and thought to be entirely benign.

Liquid metal nervesBut now, a biomedical research team led by Jing Liu of Tsinghua University in Beijing claims they’ve reconnected severed nerves using liquid metal for the first time. They claim that the metal’s electrical properties could help preserve the function of nerves while they regenerate. Using sciatic nerves connected to a calf muscle, which were taken from bullfrogs, they’ve managed to carry out a series of experiments that prove that the technique is viable.

Using these bullfrog nerves, they applied a pulse to one end and measured the signal that reached the calf muscle, which contracted with each pulse. They then cut the sciatic nerve and placed each of the severed ends in a capillary filled either with liquid metal or with Ringer’s solution – a solution of several salts designed to mimic the properties of body fluids. They then re-applied the pulses and measured how they propagated across the gap.

liquid metal nerves_1The results are interesting, and Jing’s team claim that the pulses that passed through the Ringer’s solution tended to degrade severely. By contrast, the pulses passed easily through the liquid metal. As they put it in their research report:

The measured electroneurographic signal from the transected bullfrog’s sciatic nerve reconnected by the liquid metal after the electrical stimulation was close to that from the intact sciatic nerve.

What’s more, since liquid metal clearly shows up in x-rays, it can be easily removed from the body when it is no longer needed using a microsyringe. All of this has allowed Jing and colleagues to speculate about the possibility of future treatments. Their goal is to make special conduits for reconnecting severed nerves that contain liquid metal to preserve electrical conduction and therefore muscle function, but also containing growth factor to promote nerve regeneration.

future_medicineNaturally, there are still many challenges and unresolved questions which must be resolved before this can become a viable treatment option. For example, how much of the muscle function can be preserved? Can the liquid metal somehow interfere with or prevent regeneration? And how safe is liquid metal inside the body – especially if it leaks? These are questions that Jing and others will hope to answer in the near future, starting with animal models and possibly later with humans..

Sources: technologyreview.com, arxiv.org, cnet.com, spectrum.ieee.org

The Future is Here: Self-Healing Polymer

t1000I’ve heard of biomimetics – machinery and synthetics that can imitate organic materials – but this really takes the cake! In an effort to pioneer components and devices that would posses the regenerative powers of skin, a Spanish researcher Ibon Odriozola – who works for the CIDETEC Centre for Electrochemical Technologies in Spain – has created a polymer that could lead to a future where repairing machinery is as easy as suturing an open wound.

Comprised of a poly (urea-urethane) elastomeric matrix, the material is basically a network of complex molecular interactions that will spontaneously cross-link to “heal” most any break. In this context, the word “spontaneous” means that the material needs no outside intervention to begin its healing process, no catalyst or extra reactant.

healing-polymer-headerTo experiment with the material, Odriozola cut a sample in half with a razor blade at room temperature. And in just two hours, the cut healed itself with 97% efficiency. The reaction, called a metathesis reaction, has led Odriozola to dub the material his “Terminator” polymer, in reference to you-know-who (pictured above). Though the transition process takes a little longer, and involves polymers instead of metal, the basic principle is the same.

Unlike other self-healing materials, this one requires no catalyst and no layering. In addition to being very impressive to behold, this technology can extend the life spans of plastics that are under regular stress.  The group’s main goal now is to make a harder version, perhaps one that could be formed into such parts itself. As it exists today, the polymer is squishy and somewhat soft.

???????????In addition, a good self-healing material like this is a boon for ongoing efforts to find a viable material for artificial skin. Self-healing technology could also open the door to growth materials, as new units of the matrix could be incorporated as the material stretches and tears on the microscopic level. This would be especially useful when it comes to artificial skin, since it could grow over time and remove the need for replacement.

And if the healing mechanism proves strong enough, it could even be used as an adhesive or a sealant in other materials and even electronics. Just think of it! Everything from windows, to personal devices, to joints that are in need of padding. A simple injection of this type of material, and the breaks and aches go away. And given the progress being made with androids and life-like robots, its use as a source for artificial skin could go a long way to making them anthropomorphic.

And as usual, there’s a cool demonstration video. Enjoy!


Source: extremetech.com

The Future is Here: Self-Healing Computer Chips

computer_chipIt’s one of the cornerstones of the coming technological revolution: machinery that can assemble, upgrade, and/or fix itself without the need for regular maintenance. Such devices would forever put an end to the hassles of repairing computers, replacing components, or having to buy new machines when something vital broke down. And thanks to researchers at Caltech, we now have a microchip that accomplish one of these feats: namely, fix itself.

The chip is the work of Ali Hajimiri and a group of Caltech researchers who have managed to create an integrated circuit that, after taking severe damage, can reconfigure itself in such a way where it can still remain functional. This is made possible thanks to a secondary processor that jumps into action when parts of the chip fail or become compromised. The chip is also able to tweak itself on the fly, and can be programmed to focus more on saving energy or performance speed.

computer_chip2In addition, the chip contains 100,000 transistors, as well as various sensors that give it the ability to monitor the unit’s overall health. Overall, the microchip is comparable to a power amplifier as well as a microprocessor, the kind of circuit that processes signal transmissions, such as those found in mobile phones, as well as carrying out complex functions. This combined nature is what gives it this self-monitoring ability and ensures that it can keep working where other chips would simply stop.

To test the self-healing, self-monitoring attributes of their design, Hajimiri and his team blasted the chip with a laser, effectively destroying half its transistors. It only took the microchip a handful of milliseconds to deal with the loss and move on, which is an impressive feat by any standard. On top of that, the team found that a chip that wasn’t blasted by lasers was able to increase its efficiency by reducing its power consumption by half.

healingchipGranted, the chip can only fix itself if the secondary processor and at least some of the parts remain intact, but the abilities to self-monitor and tweak itself are still of monumental importance. Not only can the chip monitor itself in order to provide the best possible performance, it can also ensure that it will continue to provide a proper output of data if some of the parts do break down.

Looking ahead, Hajimiri has indicated that the technology behind this self-healing circuit can be applied to any other kind of circuit. This is especially good news for people with portable computers, laptops and other devices who have watched them break down because of a hard bump. Not only would this save consumers a significant amount of money on repairs, replacement, and data recovery, it is pointing the way towards a future where embedded repair systems are the norm.

And who knows? Someday, when nanomachines and self-assembling structures are the norm, we can look forward to devices that can be totally smashed, crushed and shattered, but will still manage to come back together and keep working. Hmm, all this talk of secondary circuits and self-repairing robots. I can’t help but get the feeling we’ve seen this somewhere before…

t1000-ressurect_3135628_GIFSoup.com

Sources: Extremetech.com, inhabitat.com

Cool Cyborgs (updated)!

8 Man:
Always good to start with a classic, don’t you think? Especially one that really doesn’t get the attention it deserves. In addition to being Japan’s first cyborg superhero, this 60’s anime character was also the inspiration for Robocop. You heard me right!

Apparently, the main character was a Detective who was murdered by a group of ruthless criminals, but whose body was retrieved by a scientist who conducted an experimental procedure to transfer his “life force” into a machine body. Having failed the previous seven times, his eights and successful attempt is aptly named “8 Man”.

But unlike Robocop, this cyborg can do some pretty freaky stuff! In addition to being heavily armored, he can run at incredible speeds and shape-shift into other people. His true identity is kept a secret from everyone except his old police chief and the professor who conducted his experiment.

But like Robocop, 8 Man chooses to go beyond his crime-fighting mandate to find his old girlfriend, best friend and attempt to rebuild his old life. His attempts are often marred by the fact that he is no longer human, but as they say, it’s the journey that counts!

Bionic Woman:
Sure, Steve Austin was pretty cool, but did he look this good? Hell no! And in the case of the Bionic Woman, the hero story was far less crude. Though the original series was little more than a spinoff of The Six Million Dollar Man (featuring Oscar Goldman as the scientist again), the re-imagined series was far more original and endearing.

In this version, the main character (again named Jaime Sommers) is a surrogate mother and bartender struggling to make ends meet. After a near fatal car accident, she is saved by an experimental procedure involving advanced prosthetics and implants (no, not those kind!). Afterwards, she goes to work for the people who performed her operation – the Berkut Group, whom he boyfriend works for.

Through her work, she is responsible for thwarting crimes and evil machinations, while trying to explore her role and the changes she’s endured. As with the original series, Jaime’s modifications include bionic legs, a bionic right arm, a bionic right ear, and a bionic eye like that of Steve Austin. In the updated series, she also gets a dose of nanomachines called “anthrocytes” which are capable of healing her body at a highly accelerated rate.

The Borg:
Now here is a race who’s name is the second half of Cyborg! No chance for misunderstandings here! And as all fans of Star Trek know, the Borg are extremely proud of what they are. A race of beings dedicated to the perfection of life by merging the organic with the synthetic. And of course, they are all networked to a hive mind known as “the collective.”

Native to the Delta Quadrant of the Star Trek universe, the Borg occupy thousands of systems and hundreds of races. No indication is ever given where they originated from or what their intentions are, beyond adding “the biological and technological distinctiveness of other species to [their] own” in pursuit of “perfection”.

Is there a more perfect metaphor for runaway progress and the deification of technology? It’s not exactly a subtle commentary on the issue, but it does encapsulate the kinds of fear many people have when faced with a rapidly changing world that seems to be growing more complicated all the time. I imagine the Singularitarians don’t like the analogy much, but then again, Star Trek has been known to send mixed messages 😉

Cylon:
In the original series, the Cylons were lumbering, chrome covered robots that kind of resembled toasters. It was for this reason that they frequently got a shout out in the re-imagined by being referred to as such. However, the re-imagined versions were quantum leaps ahead, the result of bioengineering rather than conventional robotics.

Unlike the “skin jobs” (a reference to Blade Runner), Centurions and Cylon Raiders were only partially organic, consisting of organic brains inside machine bodies. Much the same is true of the Cylon Hybrids, the minds that operated their Basestar’s jump systems. In their case, their bodies are largely organic, but their minds are enhanced with advanced machinery and networked into their ship.

Because of this combination of organic and synthetic, Centurions and Raiders are capable of being “lobotomized”, which took place in the third season when their handlers became suspicious of their behavior. Ultimately, these three begins represented a key step in the Cylon’s evolution from mechanical to biological, which achieved perfection with the creation of the seven purely biological models.

Cyberman:
A fictional race taken from Dr. Who, these cyborgs were another one of the good Doctor’s recurring enemies. But unlike their Dalek counterparts, they seemed to change with every appearance. A possible inspiration for the Borg, these being were as humans who chose to begin experiment more and more with artificial implants.

This eventually led them to become the cold, calculated and ruthlessly logical beings that are, with every emotion all but deleted from their minds. While they do maintain their human brains and some human organs, they possess little of their original humanity, which is why they don’t get along with us decent folk!

Another parallel they share with the Borg is their means of proliferation, which is to turn other organic beings into Cybermen (a process known as “cyber-conversion”). However, they remain few in number during the course of the series and therefore prefer to act covertly, conducting their schemes from hiding places and using human pawns or robots to act in their place until they need to appear. Quite unlike the Borg, who prefer to get right in there, blow shit up, and assimilate anything that’s left!

Darth Vader:
“He’s more machine than man… twisted and evil!” That’s not to say all people who are more machine than man are evil! But it is the working definition of “cyborg.” Having lost both arms and legs in lightsaber duels and much of his body severely burned, Darth Vader (nee Anakin Skywalker) had to be put in a protective suit that regulated his breathing and bodily functions… I don’t even want to think about that!

But there was an upside to all those enhancements. For one, he got James Earl Jones vocals and the most intimidating, badass exterior in the Galaxy! Hell, even his breathing sounded scary. And it didn’t encumber his use of the Force at all, as exemplified by his ability to crush throats and toss objects around at will. And the ghosts of many dead Jedi and Luke’s missing hand can attest to it not hampering his sword fighting skills either.

Ultimately, this suit proved to be his undoing when, in the course of betraying his evil master, most of its circuits were fried by the Emperor’s electrical bolts. He died shortly thereafter, redeemed and looking upon his son for the first time “with his own eyes.” Sniff… I hate this mushy stuff!

Motoko Kusanagi:
The star of Ghost in the Shell, the beautiful, deadly and artificially enhanced Motoko Kusanagi. Known by her fellow officers as “the Major”, Kusanagi is a member of Section 9, a counter-terrorism squad working for Japan’s National Public Safety Commission. As part of her commitment to her job, Kusanagi underwent cybernetic enhancements, marrying her human brain to the “shell” that is her new body.

Throughout the original manga, anime and cinematic versions, Kusanagi’s basic role is the same. She fights all kinds of criminal elements: kingpins, warlords, and cyber terrorists, but also uses these experiences to reflect on the larger issues and her fateful choice to become a cybernetic being. These issues include what it means to be human, what constitutes life, and the line between authentic and artificial.

In addition, she’s also a pretty vivacious and good-looking being! Though technically not flesh and blood, she still maintains a pretty active sex life, at least in some versions of the story. In others, her personal life is not dealt with, but there are still plenty of nude shots, provided exposed synthetic flesh can be counted as nudity 😉

Robocop/Murphy:
Here we have another case of tragedy yielding the perfect union between man and machine. Alex Murphy, dedicated cop and family man, gets ruthlessly gunned down by a bunch of criminal thugs, only to be resurrected by a bunch of corporate thugs as a cop cyborg. Heavily armed, armored, and programmed to serve and protect, he became the Detroit Police Departments signature weapon in the war on crime.

But of course, things begin to go awry when Murphy’s memories and personality began to re-emerge. For one, there was the question of his wife and son, both of whom had been led to believe he was dead. Second, there was the psychological and emotional strain of knowing you could never be fully human again.

Alas, Murphy resolves the sacrifice of his identity and humanity by doing what he did best, kicking criminal ass and taking criminal names! These of course included crime lords, drug bosses, and the thugs who murdered him, but also the corporate crooks who created him and were plotting to take over Detroit. So aside from the sci-fi elements and human interest angles, there was also some social commentary in this franchise. Lots going on here!

Nexus Six Replicant:
“If we gift them with a past, we create a cushion or a pillow for their emotions, and consequently, we can control them better.” What is a machine when it has feelings, thoughts, and even memories?  Is it, as the Tyrell Corporation motto goes, “More human than human”?

Sure, some purists would say that a Nexus 6 isn’t technically a cyborg. But as I recall, the working definition of Cyborg is a merger of the cybernetic and organic. And as any fan of Blade Runner knows, Nexus 6’s are not so much built as grown, the product of biomedics rather than mechanics. And if that’s not good enough to get this one past the censors, screw em! Moving on…

Designed for service on the off-world colonies, every Replicant was designed to fill a certain role, ranging from military, to worker, to pleasure. In short, they could do the work of any human while simultaneously being denied the basic rights humans take for granted. However, since it was understood that they could become unruly after too much time, each unit was built with a four-year lifespan.

Inevitably, the Replicants of the movie came to Earth seeking a reprieve from their inevitable deaths. Their leader, Roy Batty, was especially obsessed with buying more time, since he himself was near the end of his lifespan. When told that there was nothing that could be done, he went a little beserk, but also came to appreciate life all the more in his last few moments.

T-800 Terminator:
“The Terminator’s an infiltration unit, part man, part machine. Underneath, it’s a hyper-alloy combat chassis – micro processor-controlled, fully armored. Very tough. But outside, it’s living human tissue – flesh, skin, hair, blood, grown for the cyborgs..” That’s how Kyle Reese, the warrior from the future, describes them. Arny’s version was a bit less… loquacious. “I’m a cybernetic organism. Living tissue over a metal endoskeleton.” Take your pick, they’re both right!

Designed to impersonate human beings, mainly so he could get close to them and kill them, the two Arny models were quite at home in the past. If you looked like this, would anyone really complain if you chose to walk the streets of LA naked? It’s LA man, anything goes! What’s more, Arny’s cyber strength and tough skeleton make him deadly and very survivable.

This proved quite the headache when one was sent back to kill Sarah Conner, but was quite a plus when one was later providing protection for her and her son! In the end, it took a hail of bullets, some well placed plastic explosives and a machine press to kill the first one. And the second one managed to survive an impalement, the loss of a limb, about a million bullets, and still managed to lay the smack down on a T-1000. Perhaps they should amend the name… Endurinators!

Thank you all! Stay tuned for the follow-up, Sexy Female Robots! I guess I’m just in a robot kind of mood 😉