The Future of Medicine: Fake Muscles and 3D Printed Implants

3d-printed-jawWhen it comes to the future of medicine, its becoming increasingly clear that biomimetics and 3D printing will play an important role. Basically, this amounts to machines that are designed to mimic biology for the sake of making our bodies run better. In addition, it means that both medical machines and organic parts could be created on site, allowing for speedier, accessible and more cost-effective interventions and augmentations.

For example, research being conducted at Harvard’s Wyss Institute for Biologically Inspired Engineering and the Harvard School of Engineering and Applied Sciences has led to the creation of artificial muscle that can imitate the beating motion of the heart – also known as the “Left Ventricle Twist”. This development, which is a big break in the field of biomimetics, could also be a game-changer when it comes to producing artificial hearts.

Artificial-Muscles-pic-1-400x267Their research started with what is known as a pneumatic artificial muscle (PAM), one which was modeled after the striated muscle fibers found in the heart. Made from silicone elastomer and embedded with braided mesh, this artificial heart was then hooked up to an air tube to see how it would handle being inflated. When air was pumped into the PAM, it responded by twisting and thus becoming shorter. This is similar to what the natural fibers of the heart do, which contract by twisting and shortening.

Several of the PAMs were then embedded within a matrix of the same elastomer from which they were made. Through a process of manipulating their orientation to one another, along with selectively applying different amounts of pressure, the researchers were able to get some of the PAMs twisting in one direction, at the same time that others twisted in the opposite direction. As a result, the silicone matrix exhibited the same three-dimensional twisting motion as the heart.

ArtificialMusclespic2-375x252The immediate applications for this are obvious; in short, creating a range of artificial hearts for patients who suffer from severe disorders or heart damage. Unlike conventional artificial hearts, these ones would be able to provide pumping action similar to the real thing. In addition, the PAMs were able to mimic the change in motion that is caused by various heart disorders, and these could be used to help in the research of such conditions, not to mention the development of treatments for them.

Equally exciting are the possibilities being offered by 3D printing which now offers a range of artificial replacements. The latest example comes from the Netherlands, where a 22-year old woman has had the top of her skull replaced with a 3D printed implant. Due to a severe condition that causes a thickening of the skull, the patient was suffering from severe and worsening symptoms. And in a first of its kind procedure, she was given a tailor-made synthetic replacement.

3d-printed-skullAs Dr. Bon Verwei of the University Medical Center (UMC) Utrecht explained, the surgery was not only a first, it was absolutely essential:

The thickening of the skull puts the brain under increasing pressure. Ultimately, she slowly lost her vision and started to suffer from motor coordination impairment. It was only a matter of time before other essential brain functions would have been impaired and she would have died. So intensive surgery was inevitable, but until now there was no effective treatment for such patients.

So far, 3D printing has been used to produce lower jaw implants, prosthetic arms, legs, and cells (kidney, liver, and skin cells). In this instance, the skull was 3D-modeled and then printed as a single full piece that was able to be slotted and secured into place. Prior to the procedure, Verwej and his team had to familiarize themselves with reconstructions and 3D printing, in particular that which pertained to partial skull implants.

3d-printed-cheekImplants have often been used when part of a skull has been removed to reduce pressure on an patient’s brain. However, Verweij claimed that cement implants are not always a good fit, and that 3D printing allows for exact specifications. As he explained it:

This has major advantages, not only cosmetically but also because patients often have better brain function compared with the old method.

Verweij worked with an Australian company called Anatomics – which uses 3D printing to produce custom-made implants and surgical models for medical practitioners – to produce the replacement skull. The surgery, only just announced, was carried out three months ago and was a success. According to Verweij, the patient has fully regained her vision and has returned to her normal life. The work undertaken on the procedure means that UMC Utrecht is now is a position to carry out other similar work.

3d-printed-skull-0The ability to tailor-make synthetic bones, which are exact duplicates to the original, offers exciting possibilities for reconstructive and replacement surgery. It also does away with some rather invasive and unsatisfactory procedures that involve putting shattered bones back together and joining them with pins, bars and screws. And considering that such procedures often require multiple operations, the combination of 3D scanning and 3D printed replacements is also far more cost effective.

And be sure to check out the video below that shows the Utrecht procedure. Be warned, the video contains actual footage of the surgery, and is therefore not recommended for the squeamish! English subtitles are also available via the video controls.


Sources:
gizmag.com, (2), wyss.harvard.edu

Top Stories of 2012

biotech_alienAs Dec. 31st fast approaches, I find myself thinking about New Years resolutions. And part of that is taking stock on what’s been accomplished in the past year. For me, one of those resolutions was to stay current and share all the new and exciting news from the field of science and tech all my followers people; to the best of my abilities, that is.

In keeping with this, I wanted to create a list of the most important developments of the last year. Many sites have produced a top 10, top 12, even a top 7, list of what they thought the most significant accomplishments were. Well, I wanted to do one of my own! Opinion varies as to what the biggest leaps and bounds were over the course of the last year, and I’ll be damned if I don’t get my say in. Lord knows I’ve spent enough time reading about them, so here’s my comprehensive list of the greatest inventions, developments and advances made during 2012.

I think you’ll all agree, the list packed with stories that are intriguing, awe-inspiring, and even a little scary! Here are the top 12, as selected by me, in alphabetical order:

3D Printing:
cartilage1As far as tech trends go, this one has been in the works for some time. However, 2012 will be remembered as the year that 3D printing truly became a reality. From tree-dimensional models to consumer products to even guns, 3D printers have been featured in the news many times over for their potential and frightening abilities.

However, one of the greatest potential uses will be in the field of artificial cartilage, organs, and even food. As the technology is refined and expands to the field of organic molecules, just about anything can and will be synthesized, leading to an era where scarcity is… well, scarce!

Bionic Implants:
mindcontrolledprostheticPerhaps the years biggest achievement came in the form of bionic prosthetics, artificial limbs which are calibrated to respond to the nerve impulses of the user. As a result, amputees, veterans and accident victims are able to receive artificial limbs that act like the real thing.

The most notable case was Zak Vawter who scaled the 103 flights of Chicago’s Willis Tower using an artificial leg. In addition, two men in Britain had their sight restored after undergoing the first ever case of retinal surgery where bionic implants were placed in their eyes.

Brain Implants:
digital-mind1In September of 2012, scientists grafted an implant onto the brain of Chimpanzee, enhancing its brain power by ten percent. This consisted of an electrode array that was attached to the cerebral cortex of several monkey subjects, researchers were able to restore and even improve their decision-making abilities.

The implications for possible therapies is far-reaching, such as with brain injuries and cognitive disorders. But additionally, it also heralds the beginning of an era where human beings will be able to enhance their intelligence, recall, and memory retention.

Commercial Space Flight:
skylonThough not yet fully realized, 2012 was a big year in terms of commercial space flight. For example, Richard Branson and Virgin Galactic announced the first successful fully-loaded “glide test” of SpaceShipTwo, the rocket craft that will be taking passengers into low orbit as soon as all the kinks are worked out of the design.

In addition, Reaction Engines announced a breakthrough with the design of their hypersonic engine, which they claim will be fitted to their proposed spaceship – the Skylon. Capable of achieving speeds of up to Mach 5, this new craft is expected to be able to take off from conventional airfields, propel itself into low orbit, and deliver supplies to the ISS and make commercial trips around the world. No telling when either company will be conducting its first real suborbital flights, but the clock is ticking down!

Curiosity Rover:
Curiosity_selfportrait
One of the years biggest announcement was the deployment of the Curiosity Rover on the Martian surface. Since it landed, the rover has provided a constant stream of scientific updates and news on the Red Planet. Though the Mars Science Team did not find the “earthshaking” proof organic molecules, it did make a number of important discoveries.

Amongst them was solid evidence that Mars was once home to large rivers and bodies of water. Furthermore, the x-ray lab on board the rover conducted studies on several rock and soil samples, determining what the chemical and mineral composition of Mars surface is.

Faster-Than-Light Travel:
alcubierre-warp-drive-overviewIn the course of speaking at the 100 Year Starship, scientists at NASA began working on the first FTL travel system ever. Long considered to be the stuff of science fiction, physicist Harold White announced that not only is the math sound, but that his team at NASA had actually started working on it.

Relying on the concept of the Alcubierre Drive, the system involves expanding and contracting space time around the ship, allowing it to move faster than the speed of light without violating the Law of Relativity.

Geo-engineering:
converted PNM file
In October, the world’s first – and illegal – act of geo-engineering took place off Canada’s West Coast. The product of a “rogue geohacker” named Russ George, who was backed by a private company, the project involved the dumping of around 100 tonnes of oron sulphate into the Pacific Ocean. This technique, known as ocean fertilization, was meant to stimulate the growth of algae which metabolize carbon and produce oxygen.

The experiment, which is in violation of two United Nations moratoria, outraged many environmental, legal, and civic groups, many of whom hail from Haida Gwaii, the traditional territory of the Haida nation, who had enlisted by George as part of a proposed “salmon enhancement project”. Though illegal and abortive, the act was the first in what may very well become a series of geoengineering efforts which will be performed the world over in order to stay the progress of Climate Change.

Google’s Project Glass:
google_glasses2012 was also the year that augmented reality became… well, a reality (oh dear, another bad pun). Back in April, Google unveiled its latest concept device for wireless and portable computing, known as Project Glass. Combining an active display matrix, a wireless internet connection and a pair of shades, Google managed to create a device that looks like something straight out of cyberpunk novel.

HIV and Flu Vaccines:
HIV-budding-ColorWhen it comes to diseases, HIV and the Flu have two things in common. Until 2012, both were considered incurable, but sometime in the near future, both could be entirely preventable. In what could be the greatest medical breakthroughs in history, 2012 saw scientists and researchers experiment with antibodies that have been known to fight off HIV and the flu, and to good effect.

In the former case, this involved using a new process known as Vectored ImmunoProphylaxis (VIP), an inversion of the traditional vaccination method, where antibodies were introduced to mice. After allowing the antibodies to reproduce, researchers at Caltec found that the mice were able to fight off large quantities of the virus. In the latter, researchers at the Friedrich-Loeffler Institute in Riems Island, Germany used a new RNA-based vaccine that appeared to be able to fight off multiple strains of flu, not just the latest mutation.

Taken together, these vaccines could bring an end to a common, but potentially deadly ailment, and signal the end of the plague of the 20th century. In addition, this could be the first in a long series of developments which effectively brings all known diseases under our control.

Medical Implants:
enhancement2012 also saw the culmination of several breakthroughs in terms of biomedical research. In addition to the world’s first medimachine, there were also breakthroughs in terms of dissolving electronics, subdermal implants that dispense drugs, and health monitoring patches.

Little wonder then that Cambridge University announced the creation of the Center for the Study of Existential Risk to evaluate future technologies, or that Human Rights Watch and Harvard University teamed up to release a report calling for the ban of “killer robots”. With all the potential for enhancement, it could be just a matter of time before non-medical enhancements are a reality.

Mind-controlled prostheses:
woman-robotic-arm_650x366Researchers at BrainGate created a brain-machine interface that allows users to control an external device with their minds. The first person to use this revolutionary new system was Cathy Hutchinson, a stroke victim who has been paralyzed from the neck down for 15 years, who used the robotic arm to drink a cup of coffee.

This news, combined with other advances in terms of bionic prostheses, could signal the end of disability as we know it. Henceforth, people with severe injuries, amputations and strokes could find themselves able to make full recoveries, albeit through the use of robotic limbs.

Self-driving cars:
googlecar2012 marked an important year as three states (California, Nevada, and Florida) made autonomous vehicles legal. Self-driving cars, once perfected and produced en masse, will help with traffic congestion and significantly reduce the chance of auto accidents through the use of GPS, radar, and other technologies.

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All in all, it’s been an exciting year. And with all that’s been accomplished, the future is certainly looking a lot more interesting and even frightening. What is clear is that predictions made for some time now are becoming realizable, including replication, a cure for all known diseases, advanced robotics, implants, cybernetics, and even post-humanism. Regardless of where one sits on these developments, be you pro, con, or neutral, I think we can all agree that it is an exciting time to be alive!

Happy New Year to all, and here’s hoping 2013 proves just as interesting, and hopefully a lot more peaceful and sound. And may we ALL find ourselves able to keep our New Years resolutions and build upon all we’ve accomplished so far. And of course, with all the potential for medical and technological enhancements that are coming, I sincerely hope we can find ways to improve ourselves on a personal level too!