Tag: biohacking

Immortality Inc: Google’s Kurzweil Talks Life Extension

calico-header-640x353Human life expectancy has been gradually getting longer and longer over the past century, keeping pace with advances made in health and medical technologies. And in the next 20 years, as the pace of technological change accelerates significantly, we can expect life-expectancy to undergo a similarly accelerated increase. So its only natural that one of the worlds biggest tech giants (Google) would decide to becoming invested in the business of post-mortality.

As part of this initiative, Google has been seeking to build a computer that can think like a human brain. They even hired renowed futurist and AI expert Ray Kurzweil last year to act as the director of engineering on this project. Speaking at Google’s I/O conference late last month, he detailed his prediction that our ability to improve human health is beginning to move up an “exponential” growth curve, similar to the law of accelerating returns that governs the information technology and communications sectors today.

raykurzweilThe capacity to sequence DNA, which is dropping rapidly in cost and ease, is the most obvious example. At one time, it took about seven years to sequence 1% of the first human genome. But now, it can be done in a matter of hours. And thanks to initiatives like the Human Genome Project and ENCODE, we have not only successfully mapped every inch of the human genome, we’ve also identified the function of every gene within.

But as Kurzweil said in the course of his presentation – entitled “Biologically Inspired Models of Intelligence” – simply reading DNA is only the beginning:

Our ability to reprogram this outdated software is growing exponentially. Somewhere between that 10- and 20-year mark, we’ll see see significant differences in life expectancy–not just infant life expectancy, but your remaining life expectancy. The models that are used by life insurance companies sort of continue the linear progress we’ve made before health and medicine was an information technology… This is going to go into high gear.

immortality_dnaKurzweil cited several examples of our increasing ability to “reprogram this outdated data” – technologies like RNA interference that can turn genes on and off, or doctors’ ability to now add a missing gene to patients with a terminal disease called pulmonary hypertension. He cited the case of a girl whose life was threatened by a damaged wind pipe, who had a new pipe designed and 3-D printed for her using her own stem cells.

In other countries, he notes, heart attack survivors who have lasting heart damage can now get a rejuvenated heart from reprogrammed stem cells. And while this procedure awaits approval from the FDA in the US, it has already been demonstrated to be both safe and effective. Beyond tweaking human biology through DNA/RNA reprogramming, there are also countless initiatives aimed at creating biomonitoring patches that will improve the functionality and longevity of human organs.

avatar_imageAnd in addition to building computer brains, Google itself is also in the business of extending human life. This project, called Calico, hopes to slow the process of natural aging, a related though different goal than extending life expectancy with treatment for disease. Though of course, the term “immortality” is perhaps a bit of misnomer, hence why it is amended with the word “clinical”. While the natural effects of aging are something that can be addressed, there will still be countless ways to die.

As Kurzweil himself put it:

Life expectancy is a statistical phenomenon. You could still be hit by the proverbial bus tomorrow. Of course, we’re working on that here at Google also, with self-driving cars.

Good one, Kurzweil! Of course, there are plenty of skeptics who question the validity of these assertions, and challenge the notion of clinical immortality on ethical grounds. After all, our planet currently plays host to some 7 billion people, and another 2 to 3 billion are expected to be added before we reach the halfway mark of this century. And with cures for diseases like HIV and cancer already showing promise, we may already be looking at a severe drop in mortality in the coming decades.

calico1Combined with an extension in life-expectancy, who knows how this will effect life and society as we know it? But one thing is for certain: the study of life has become tantamount to a study of information. And much like computational technology, this information can be manipulated, resulting in greater performance and returns. So at this point, regardless of whether or not it should be done, it’s an almost foregone conclusion that it will be done.

After all? While very few people would dare to live forever, there is virtually no one who wouldn’t want to live a little longer. And in the meantime, if you’ve got the time and feel like some “light veiwing”, be sure to check out Kurzweil’s full Google I/O 2014 speech in which he addresses the topics of computing, artificial intelligence, biology and clinical immortality:


Sources: fastcoexist.com, kurzweilai.net

Building the Future: 3D Printing and Silkworms

arcology_crystalWhen it comes to building the homes, apartment blocks and businesses headquarters of the future,  designers and urban planners are forced to contend with a few undeniable realities. No only are these buildings going to be need to be greener and more sustainable, they will need to be built in such a way that doesn’t unnecessarily burden the environment.

Currently, the methods for erecting a large city building are criminally inefficient. Between producing the building materials – concrete, steel, wood, granite – and putting it all together, a considerable amount of energy is expended in the form of emissions and electricity, and several tons of waste are produced.

anti-grav3d2Luckily, there are many concepts currently on the table that will alter this trend. Between using smarter materials, more energy-efficient design concepts, and environmentally-friendly processes, the future of construction and urban planning may someday become sustainable and clean.

At the moment, many such concepts involve advances made in 3-D printing, a technology that has been growing by leaps and bounds in recent years. Between anti-gravity printers and sintering, there seems to be incredible potential for building everything from settlements on the moon to bridges and even buildings here on Earth.

bridge_3One case in particular comes to us from Spain, where four students from the Institute for Advanced Architecture of Catalonia have created a revolutionary 3-D printing robot. It’s known as Stone Spray, a machine that can turn dirt and sand into finished objects such as chairs, walls, and even full-blown bridges.

The brainchild of Anna Kulik, Inder Prakash, Singh Shergill, and Petr Novikov, the robot takes sand or soil, adds a special binding agent, then spews out a fully formed architectural object of the designers’ choosing. As Novikov said in an interview with Co.Design:

The shape of the resulting object is created in 3-D CAD software and then transferred to the robot, defining its movements. So the designer has the full control of the shape.

robot-on-site_0So far, all the prototypes – which include miniature stools and sculptures – are just 20 inches long, about the size of a newborn. But the team is actively planning on increasing the sizes of the objects this robot can produce to architectural size. And they are currently working on their first full-scale engineering model: a bridge (pictured above).

If successful, the robot could represent a big leap forward in the field of sustainable design. Growing a structure from the earth at your feet circumvents one of the most resource-intensive aspects of architecture, which is the construction process.

And speaking of process, check out this video of the Stone Spray in action:


At the same time, however, there are plans to use biohacking to engineer tiny life forms and even bacteria that would be capable of assembling complex structures. In a field that closely resembles “swarm robotics” – where thousands of tiny drones are programmed to build thing – “swarm biologics” seeks to use thousands of little creatures for the same purpose.

silkpavilionMIT has taken a bold step in this arena, thanks to their creation by the Mediated Matter Group that has rebooted the entire concept of “printed structures”. It’s called the Silk Pavilion, a beautiful structures whose hexagonal framework was laid by a robot, but whose walls were shell was created by a swarm of 6,500 live silkworms.

It’s what researchers call a “biological swarm approach to 3-D printing”, but could also be the most innovate example of biohacking to date. While silkworms have been used for millennia to give us silk, that process has always required a level of harvesting. MIT has discovered how to manipulate the worms to shape silk for us natively.

silkpavilion-2The most immediate implications may be in the potential for a “templated swarm” approach, which could involve a factory making clothes just by releasing silkworms across a series of worm-hacking mannequins. But the silkworms’ greater potential may be in sheer scale.

As Mediated Matter’s director Neri Oxman told Co.Design, the real bonus to their silkworm swarm its that it embodies everything an additive fabrication system currently lacks. 

It’s small in size and mobile in movement, it produces natural material of variable mechanical properties, and it spins a non-homogeneous, non-woven textile-like structure.

What’s more, the sheer scale is something that could come in very handy down the road. By bringing 3-D printing together with artificial intelligence to generate printing swarms operating in architectural scales, we could break beyond the bounds of any 3-D printing device or robot, and build structures in their actual environments.

silkpavilion-1In addition, consider the fact that the 6,500 silkworms were still viable after they built the pavilion. Eventually, the silkworms could all pupate into moths on the structure, and those moths can produce 1.5 million eggs. That’s enough to theoretically supply what the worms need to create another 250 pavilions.

So on top of everything else, this silkworm fabrication process is self-propagating, but unlike plans that would involve nanorobots, no new resources need to be consumed to make this happen. Once again, it seems that when it comes to the future of technology, the line between organic and synthetic is once more blurred!

And of course, MIT Media Lab was sure to produce a video of their silkworms creating the Silk Pavilion. Check it out:


Sources: fastcodesign.com, (2)

Glowing Plants and the Future of Gene Patenting

DNA-1Synthetic biology – also known as biohacking – is an emerging and controversial scientific field that uses gene-writing software to compile DNA sequences. And thanks to a recent ruling handed down by the US Supreme Court, it is a process which is now entirely legal. All told, the potential applications of synthetic biology are largely useful, leading to lifesaving cures, or altered crops that survive in any environment.

However, there are numerous potential (and potentially harmful) commercial applications that could emerge from this as well. One such advancement comes from a DIY synthetic biology lab known as Glowing Plant, one that specializes in synthetic bio hacking. Basically, the project was one of many that emerged out of Singularity University – a research institute dedicated future technologies today.

glowing_plantsGlowing Plant was  originally created to show the power of DIY synthetic biology, and has since sets its sights on developing a species of glowing house plant for consumers. To fund their goal, they opened up a Kickstarter campaign – the first of its kind – with the goal of $65,000. Based on research from the University of Cambridge and the State University of New York, the Glowing Plants campaign promised backers that they would receive seeds to grow their own glowing Arabidopsis plants at home.

glowing_plants2Glowing Plant also announced that if the campaign reaches its $400,000 stretch goal, glowing rose plants will also become available. As of the publication of this article, they passed that goal with a whopping $484,013 from a total of 8,433 backers. It seems there are no shortage of people out there who want to get their hands on a glowing house plant.

But Glowing Plant, the laboratory behind the project, has no intention of stopping there. As Antony Evans, co-founder of the project explained:

We wanted to test the idea of whether there is demand for synthetic biology projects. People are fundamentally excited and enthusiastic about synthetic biology.

Given the thousands of people backing the project, I’d say he’s right! But rest assured, Evans and his team have no intention of stopping there. The ultimate goal is to create larger species of glowing plants.

glowing_plants1The method used to achieve this is really quite interesting. It starts with the team downloading the luciferase-lucifern genes – the firefly DNA that allows them to glow – into a Genome Compiler, and then rewiring the DNA so that the proteins can be read by plants. The DNA sequences are then sent off to DNA printing company Cambrian Genomics, which has developed a relatively low-cost laser printing system. Those sequences are printed, put on a little spot of paper, and mailed back to the team.

After that, the team relies on one of two methods to transmit the firefly DNA into the Arabidopsis’ themselves. One way is to use a bacteria solution that is capable of injecting its own DNA into plants and rewriting theirs, which then causes the altered plants to germinate seeds of the new glowing strain. The other involves gold nano-particles coated with a DNA construct that are then fired at the plant cells, which are then absorbed into the plant chromosomes and alters their DNA.

NanoparticlesThis second method was devised to do an end run around specific Department of Agriculture regulations that govern the use of viruses or other pathogens to modify DNA. Though technically legal, the process has attracted resistance from environmental groups and the scientific community, fearing that the DNA of these altered plants will get into the natural gene pool with unknown consequences.

In fact, an anti-synthetic biology group called ECT has emerged in response to this and other such projects – and is centered in my old hometown of Ottawa! They have countered Glowing Plant’s Kickstarter campaign (which is now closed) with a fundraising drive of their own, entitled “Kickstopper”. In addition, the group has started a campaign on Avaaz.org to force the Supreme Court to reconsider the ruling that allows this sort of bioengineering to take place.

At present, their fundraising campaign has raised a total of  $1,701 from 58 backers – rougly 9% of its overall goal of $20,000 – and their Avaaz campaign has collected some 13,000 signatures. With 36 days left, there is no telling if they’re efforts will succeed in forcing a legal injunction on Glowing Plant, or if this is the first of many synthetic biology products that will make it to the market through private research and crowdfunding.

A fascinating time we live in, and potentially frightening…

Sources: fastcoexist.com, (2), kickstarter.com, glowingplant.com

DIY Prosthetics on Demand

DIY_prostheticThe field of prosthetics has seen some rather stark and amazing developments in recent years. And considering the rise in DIY cybernetics, biohacking and 3D printing, it was just a matter of time before a bunch of hobbyists found a way to create their own. And that’s precisely what Ivan Owen and Richard Van, a special effects artist and a woodworker, have managed to do.

Despite living hundreds of kilometers from each other, these two men managed to collaborate on the creation of an artificial limb. And in an especially heartwarming twist, they did it on demand for a South African boy named Liam who war born without fingers on his right hand. For some time, they had been working together to create prosthetics relying only on their general know-how and technology that is available to the general public, all the while keeping tabs on their progress and sharing it with the general public through their blog comingupshorthanded.com.

DIY_prosth_LiamAfter stumbling onto this website, Liam’s mother contacted Ivan and Richard and asked if they could create an artificial hand for her son. They obliged and, using a 3D printer, bits of cable, bungee cord returns and rubber thimbles, the two men collaborated over the internet to make it happen. And not only have they changed the life of young Liam, who is capable of doing things he never thought possible, they now hope to do the same for others looking for low-cost prosthetic alternatives.

For years, these two had been working on a “Robohand” together, in part due to the fact that Van As lost his right hand fingers in a woodworking accident. But until now, they had not considered the wider implications of their work. And after talking to Liam’s mom and seeing the difference it made in Liam’s life, they have set up a fundraising page are take requests for people looking for devices or who are interesting in offering help. Thanks to the open-source nature of the project, a number of improvements have already been made to their designs, with more sure to follow.

bionic_handsIn addition to showcasing the trend of DIY device-making and open-source development, this is also good news for anyone in the market for an artificial hand or limb and who does not have $10,000 kicking around. That’s the standard price for a prosthetic these days, which despite incredible leaps in terms of sophistication have not gotten any cheaper! But with the right know-how, and some technical assistance, a person can find their way to a cheap, printed alternative and see similar results.

Overal, prosthetics offer people the opportunity to restore mobility and retain their independence. And now, thanks to the internet and 3D printing capabilities, they can manufacture these devices independently. The power to restore your own mobility is in your own hands… Interesting, and one might even say cosmically convergent!

Rock on Liam! You’ve got a great mom and some talented friends. As for the rest of you, be sure to check out this video of the 5 year old boy in action with his new prosthetic hand.

Source: IO9.com, comingupshort.com, fundly.com

Of DIY Cybernetics and Biohacking

transhuman3It seems that biohackers and enthusiasts of body augmentation could be setting a new trend, and doing it all from the comfort of their basements. That’s the essence of an article filed by Neal Ungerleider this past September, in which he stated that biohackers have not only cloned the innovation strategies of Silicon Valley, but could also be reshaping how technology is being created.

Amongst their efforts are such things as brain interfaces that can control video games with human thoughts, Bluetooth sensors that are meant to go under the skin and send vital signs to mobile phones, tissue engineering that can create in vitro “steaks” and leather, and devices that convert brainwaves into actual speech. These efforts are collaborative in nature and connect numerous basements, labs and research facilities together to share research, resources, and breakthroughs.

Those who take an active part in this trend are often known as grinders or biohackers, people who have chosen not to wait for cybenetic enhancements and body augmentation to become commercially available and seek to create them on their own.

According to Ungerleider:

“West Coast biohackers and grinders were the pioneers of this tech-driven, California brand of utopianism… For biohackers everywhere, augmentation of humanity itself—whether through technology or more traditional methods—is the primary goal. Common conversation points include DIY cyborgs, the quantified self, and diet…

“But a growing community on the East Coast—in greater New York, Boston, and Pittsburgh—is synthesizing Silicon Valley’s entrepreneurial DNA for its unique innovation model. Experimentation and science here is not only an exercise in advancing humanity through tech but is often applied toward creating viable cybernetic products for the market.”

One such group is Biohackers NYC, a group that was formed in 2012 largely in response to all the innovation that was taking place on the opposite coast. In additi0n to the initial startup group, it was joined by numerous startups, incubators, and workspaces scattered across the outer boroughs. As group founder and psychiatrist Lydia Fazzio claimed in an interview back in September:

“Our intent was to cover the spectrum of biohacking from manipulating non-human genomes to also the body and the mind. It’s a holistic approach to the meaning of biohacking, whether technology or nutrition. However you get there, we all have the innate potential to be an optimal functioning human in society. Our question is: How do we get there?”

davinci_transhumanOne of the attractions of this new movement is that it allows the merger of skilled professionals and dedicated hobbyists a chance to collaborate on projects of mutual interest. It also takes advantage of new business and development models – i.e. crowdsourcing – which is made possible thanks to the digital revolution.

Already, message boards have sprung up that allow disparate “labs” to post information on their work and share with others who have similar interests and projects on the go. These include DIYbio, which deals with the larger field of DIY biotechnology labs; and biohack.me, where the possibilities of subdermal bone conduction headphones and echolocation implants are being contemplated.

TranshumanIn the end, this is really just a small part of a much larger movement, which takes on various names. On is transhumanism, a movement which believes that human limitations can and must be transcended with the help of technological innovation. Another is Singularitarianism, a movement popularized by such Futurists as Ray Kurzweil. These individuals believe that technology will (or has) reached the point where human beings can take control of their own mortality, abilities and evolution. While some are willing to wait, others are intent on making it happen sooner other than later.

Naturally, there is a great deal of skepticism towards this new trend. For one, there are countless people who believe it to be the stuff of “science fiction”, and not real science. But, as Ungerleider claims, this represents the culmination of trends that have been in the works for some time. What’s more, it represents the monetization and mass marketing of technologies which have been under development for many years. And in truth, the line between science fiction and science fact has always been a fine one. All that’s ever been needed for us to transcend it is for people to make it happen.

Sources: fastcompany.com, Wired.com, IO9.com